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w\ɂݿ޼ޱ݌nݿ޼ޱ݌nڷe̝hR°َ_nR˽ݖȂǂɕނ顂ڷe̝hRƍR˽ݖGABAAeɍp܂܊ԂŌʂ߂p額pԂɂ褒Zԍp^Zԍp^ԍp^ԍp^ɕނ顂ق̎ނ̐ݎêɍp݂ݎe̍쓮Ƃ°َ_n̖ÎwႭ݂ł͉ߗʕ̊댯lƎgp͐Ȃ[2]°َ_n̊댯̂ߤ1960Nɂݿ޼ޱ݌n嗬ƂȂɂŠO1980Nɔݿ޼ޱ݌noꂵ̔ݿ޼ޱ݌nݿ޼ޱ݌nƑ傫ȍꂸ݂ł͖򕨗Ö@ȊO̕@ɒڂ[3]

pƂĤGABAêɍp鐇ɂ͈ˑ`̂قp̋LȂYiLQjLȂԂł̎Ԃ̉^]Ȃǂ̖VsN̖CȂǂ顂܂Ɉߐ̌YE}sȂǂgݍ킳ٔ𐶂題YԂŎE}sႪ[4]ꍇɂꂪٔłƂʂɂ°َ_n[5]ݿ޼ޱ݌n[6][7]ݿ޼ޱ݌nݍ쓮[8]̎gp͗}Ǐ𑝉1996NɂͤEی@ւݿ޼ޱ݌n̢Iȗp30܂łłƂĂ[9]܂E̊댯𑝉邽ߐTdȊĎƤE̋ꤕˑTasł͓ʂȒӂKvł褏ƂĂ琔TԂƂĂ[10]Ԃɓn鏈sꍇ顐̒IȎgp͎Sؽ߂邱Ƃ؂Ă[11][12][13][14]jƂɤ̎gpȆɌт‚Ă邱Ƃ炩ɂȂĂ[12]Qsׂ̊댯߂܂[15]

̑͋KΏەł1971N_Ɋւz°َ_nݿ޼ޱ݌n̑ͤp̊댯邽߂ɤۏ̕t\iޭفjIIIIVɎw肳ꗬʂ顱ضłK@ɂēlɕt\ɂĒ߂Ă顓{ɂĂऍۏyĂ邽yь_@ɂĤ2_ɂ°َ_nݿ޼ޱ݌n׾3_ɂ͂قݿ޼ޱ݌nݿ޼ޱ݌n̑߂Ă[16]2_͕t\III3_ɕt\IVɑ2010Nۖ򓝐ψͤ{łݿ޼ޱ݌n̏ʂ̑̌ɤtɂsK؂ȏƂĂ[17]ɉ2010Nɓ{4wŊ댯ܑʏɒӊNĂ󋵂ł[18][19][20]ˑǂ̊댯ɂ‚ĂtmȂꍇ邱Ƃ񍐂Ă[21]

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1869Nɂװꤐ̂߂ɗpꂽ1900N°َ_noꂷƤuĂ[22]

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1960Nɂͤݿ޼ޱ݌n̖܂̔

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̎ނ̖Ɍ炸ƓIɐiɗގii݌v擾̔̂͐Ђ̐헪ł[26]Ђंގ̉޽ľװƂȂޱ̒Ɋ܂܂[26]

1960NɂͤIɍp܂褌ċz}ĎS邱ƂmĂ邽ߊ댯ƂĂ°َ_nݿ޼ޱ݂ƤٺقƂϐoꤎ悤ȕʂɍpĂ̂ł͂Ȃƍlꂽ[27]ɌiނGABAêɍpĂ邱Ƃ炩ɂȂ[27]

1969NɤDޭިްٺقݿ޼ޱ݂̑pŎSƤض@̒ψĂ[26]1971Nɂͤ܂߂܂̗p̊댯h~邽߂_Ɋւzꂽضł1975Nɂͤݿ޼ޱ݌nͽޭIVɎw肳ZԂɌF߂ꂽ[26]

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1980Nɤݿ޼ޱ݌n̐򂪓oꂵقƂǂ̗ՏSƗLTԂ܂ł؂ĂȂ[31]ɤ̎gpS̊댯𑝉Ƃ񍐂‚Ȃꂽ[31]
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ضRł̎gp[ҏW]

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Ashton, Heather (2002-08) (pdf). ݿ޼ޱ | ͂ǂ̂悤ɍpEɂ͂ǂ΂悢 (Report). Professor C H Ashton. http://www.benzo.org.uk/amisc/japan.pdf 2013N119{. 
WHO Programme on Substance Abuse (1996-11) (pdf). Rational use of benzodiazepines - Document no.WHO/PSA/96.11 (Report). World Health Organization. http://whqlibdoc.who.int/hq/1996/WHO_PSA_96.11.pdf 2013N310{. 
صĥSާݽ݁w_͔]̕aCHx_Ė󤒆ˌq݂[2008N2Blaming the Brain, 1998
޲ިޥ˰ذwR–̌߁xcĖJ_Ŕ݂[2005N8Let Them Eat Prozac, 2003
޲ިޥ˰ذw˰ذ_ȎÖ޲ށxc]dKĖ~q݂[2009N75šPsychiatric drugs explained: 5th Edition
pËZp]@\ (2004-04). Insomnia - newer hypnotic drugs (TA77) (Report). National Institute for Health and Clinical Excellence. http://www.nice.org.uk/TA077 2013N310{. 
JȈHiNJĎw΍ (2012-02) (pdf). a@fÏɂ_戵̎ (Report). http://www.mhlw.go.jp/bunya/iyakuhin/yakubuturanyou/dl/kouseishinyaku_01.pdf 2013N310{. 
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ݿ޼ޱ݌n

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